Hyperthermic intraperitoneal chemotherapy in advanced ovarian cancer

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Hyperthermic intraperitoneal chemotherapy (HIPEC) in ovarian cancer.

Ovarian cancer remains the fourth leading cause of cancer death in women in France. It is all too often diagnosed at an advanced stage with peritoneal carcinomatosis (PC), but remains confined to the peritoneal cavity throughout much of its natural history. Because of cellular selection pressure over time, most tumor recurrences eventually develop resistance to systemic platinum. Options for sa...

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Hyperthermic intraperitoneal chemotherapy for ovarian cancer: is there a role?

women despite the fact that, paradoxically, it has innate characteristics which should facilitate effective treatment: it begins, and frequently remains, confined within the peritoneal cavity for much of its natural history (apart, most notably) from retroperitoneal lymph node involvement, it is relatively 'non-invasive' and thus amenable to surgical resection, and it responds well to initial c...

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Cytoreductive Surgery Combined with Hyperthermic Intraperitoneal Intraoperative Chemotherapy in the Treatment of Advanced Epithelial Ovarian Cancer

Background/Aims. Intraperitoneal intraoperative hyperthermic chemotherapy (HIPEC) has been used in the treatment of ovarian cancer. The purpose of the study is to determine the efficacy of HIPEC after cytoreductive surgery in advanced ovarian cancer. Patients/Methods. From 2006 to 2010 patients with advanced ovarian cancer were enrolled in a prospective nonrandomized study to undergo cytoreduct...

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Hyperthermic intraperitoneal chemotherapy: another choice for advanced gastric cancer?

Gastric cancer is one of the most common cancers throughout the world. Overall, the prognosis of gastric cancer is very poor, and surgery is the main treatment modality for this deadly disease. Standard gastrectomy with D2 dissection is the principal surgical procedure performed with curative intent. However, survival rates after curative surgery for gastric cancer are disappointing. Many patie...

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Hyperthermic intraperitoneal chemotherapy with cisplatin and paclitaxel in advanced ovarian cancer: a multicenter prospective observational study

OBJECTIVE Cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) have been recently reported with favorable oncological outcomes as treatment of advanced epithelial ovarian cancer (EOC). The aim of this study was to demonstrate the feasibility of CRS+HIPEC with cisplatin and paclitaxel for the treatment of advanced EOC. METHODS This is a prospective observational st...

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ژورنال

عنوان ژورنال: Journal of Gynecologic Oncology

سال: 2018

ISSN: 2005-0380,2005-0399

DOI: 10.3802/jgo.2018.29.e51